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Science in 2026: what to expect this year

Nature, Published online: 01 January 2026; doi:10.1038/d41586-025-04114-0 More refined AI models, advancements in human gene editing and the continuing impact of the Trump Team on

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Random heteropolymers as enzyme mimics

Breslow, R. Artificial enzymes. Science 218, 532–537 (1982). Article  ADS  PubMed  CAS  Google Scholar  DeGrado, W. F., Wasserman, Z. R. & Lear, J. D. Protein

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Seeding opportunities for Black atmospheric scientists

Vernon Morris (outlined) with alumni from the atmospheric sciences PhD programme he established at Howard University in Washington DC.Credit: Vernon Morris Changemakers This Nature Q&A

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The Nature Podcast highlights of 2025

You have full access to this article via your institution. Download the Nature Podcast 24 December 2025 In this episode: 00:40 What a trove of

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Explore 2025 with Leif Penguinson

For five years now, Briefing readers have eagerly awaited Fridays for a chance to put their penguin-hunting skills to the test. Each week, Leif Penguinson,

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peer reviews created using AI can avoid detection

The difficulty of detecting AI-tool use in peer review is proving problematic.Credit: BrianAJackson/iStock via Getty It’s almost impossible to know whether a peer-review report has

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I’ve earned my PhD — what now?

Illustration: David Parkins The problem Dear Nature, In December 2024, I finished my PhD in biomedical chemistry in Italy, and I now find myself in

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Revised estimates of CO<sub>2</sub> sources and sinks improve global carbon accounting

Nature, Published online: 12 December 2025; doi:10.1038/d41586-025-03981-x Updated estimates of the worldwide sources and sinks of anthropogenic carbon dioxide provide a firmer basis for monitoring

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Pancreatic cancer is evasive. Is the nervous system the reason why?

The neural network in a healthy pancreas (left) and in a pancreatic tumour (right).Credit: Ref. 4 When Jami Saloman gave capsaicin, the molecule that gives

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AI is saving time and money in research — but at what cost?

More than 60% of researchers surveyed about AI say they use it for work.Credit: MD Abu Sufian Jewel/NurPhoto via Getty Scientists are increasingly using artificial